NUWIQ Convenient and Flexible Dosing

NUWIQ offers physicians and nurses the convenience of flexible dosing for children and adults, and a wide range of dosage strength vials with the lowest, 2.5 ml diluent volume among currently approved FVIII products.

NUWIQ dosing for routine prophylaxis in children and adults1

Patients Dose (IU/kg) Frequency of Infusions
Adolescents (12-17) and adults 30-40 Every other day
Children (2-11 years) 30-50 Every other day or 3 times per week

NUWIQ dosing for on-demand treatment and control of bleeding in children and adults

Type of Bleeding Episodes Required Peak Post-Infusion factor VIII Activity (% of Normal or IU/dL) Frequency of Dosing (hours) Duration of Therapy (days)
Superficial muscle or soft tissue and oral bleeds
20-40 12-24 At least 1 day, until the bleeding episode of resolved
Moderate to Major
Hemorrhage into muscles, into oral cavity, hemarthrosis, known trauma
30-60 12-24 for 3-4 days or more until the bleeding episode is resolved
Intracranial, intra-abdominal, gastrointestinal or intrathoracic bleeds, central nervous system bleeds, bleeding in retropharyngeal spaces or iliopsoas sheath, eyes, retina, fractures, or head trauma.
60-100 8-24 Until bleeding risk is resolved


Dosing Flexibility with NUWIQ

  • NUWIQ offers a broad range of dosage strengths with the lowest, 2.5 ml diluent volume among currently approved FVIII products.
  • Available in 250 IU, 500 IU, 1000 IU, 1500 IU, 2000 IU, 2500 IU, 3000 IU, and 4000 IU vials
  • Larger single-dose vials of 2500, 3000 and 4000 IU offer greater flexibility and convenience for patients requiring larger volumes of FVIII.
  • All NUWIQ vial sizes are reconstituted with an easy-to-use 2.5 ml syringe, pre-filled with water for injection.
  • Each NUWIQ box comes with a vial adapter, butterfly needle, and alcohol swabs in addition to the NUWIQ vial and pre-filled syringe.

NUWIQ device and packaging
NUWIQ device and packaging

Storing NUWIQ

  • Keep NUWIQ in its original box in the refrigerator to protect it from exposure to light
    • NUWIQ can be stored in the refrigerator for up to 24 months at 36-46°F (2-8°C)
    • NUWIQ can be kept at room temperature (up to 77°F [25°C]) for a single period not exceeding 3 months
    • After being stored at room temperature, NUWIQ must not be put back into the refrigerator
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Personalized prophylaxis has the potential to improve care and enable fewer infusions for your patient

Find out if personalized prophylaxis with NUWIQ is right for your patients.
  1. NUWIQ full Prescribing Information. Paramus, NJ: Octapharma; rev 2021.