NUWIQ® – A Natural Choice for Patients with Hemophilia A

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What is NUWIQ?

NUWIQ is a recombinant Factor VIII (rFVIII) for the treatment of adults and children with Hemophilia A that’s produced in a human cell line, not hamster cell line1,2. In fact, NUWIQ is the first and only rFVIII produced in a human cell line without chemical modification or protein fusion. We call it ‘A Natural Choice’.

  • The rFVIII protein produced in a human cell line closely resembles the FVIII the body produces naturally3
  • May help reduce the risk of forming neutralizing antibodies (inhibitors) to FVIII.3
  • FVIII replacement therapy has been proven to be safe and effective over decades of use4.
  • The ability to accurately measure FVIII levels with routine laboratory tests, like the chromogenic and one-stage assays, has helped make FVIII treatment the standard of care for Hemophilia A.

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NUWIQ is the first and only rFVIII produced in a human cell line without chemical modification or protein fusion.

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References
  1. Sandberg H, et al. Thromb Res.2012;130:808-817.
  2. Casademunt E, et al. Eur J Haematol. 2012;89:165-176.
  3. Kannicht C, et al. Thromb Res. 2013;131:78-88.
  4. Cafuir LA, Christine L. Kempton CL. Ther Adv Hematol. 2017;8(10):303–313.
  5. NUWIQ full Prescribing Information. Paramus, NJ: Octapharma; rev 2021.
  6. Lissitchkov T, Rusen L, Georgiev P, et al. Haemophilia. 2017;23:697-704.